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Multi drug resistant organisms (MDRO), a technical definition that is not uniform, refers to microbes that are resistant to many antimicrobial agents from different classes and inhibitory mechanisms. MDRO infections have clinical manifestations that are like infections caused by susceptible pathogens, with an exception in several cases.
Chest pain is one of the leading presentations in the Emergency Department (ED), and the historically conservative approach to avoid missing a potential acute myocardial infarction (AMI) has led clinicians to admit or prolong the ED dwell time of many more patients than are subsequently found to have an AMI.
Human intestinal microbiota is the most studied microbial community; it is complex and intensely related to its host (human). Intestinal microbiota is thought to have a role in many pathological conditions in human, and evidence supporting such theory is increasingly improving.
Rising medical costs have become a huge social burden throughout the world, having grown four to five times on average during the past three decades. The situation in the U.S. has been the most extreme with eight to nine times in growth rate, translated into total medical costs that totalled $3 trillion, amounting to 17.8 per cent of the gross domestic product in 2015.
Over a decade ago, predictions were made about the rapid growth of data on the World Wide Web, and the ability to gain meaningful insight from this information.
Only a few years ago the term digital pathology implied a static snapshot obtained from a digital camera mounted on a conventional microscope, and telepathology implied remotely viewing a microscope slide via an analogue camera.
Itchy, scaly, painful, unseemly and all-round unpleasant, fungal skin and nail infections are a scourge of our times. They are caused predominantly by dermatophytes, but also by yeasts and moulds. The pathogens spread easily via contaminated surfaces such as clothes, shoes, showers, floors and carpets, as well as by direct contact.
Moving towards consolidation, standardisation and automation in the laboratory to tackle today’s challenges and tomorrow’s complex healthcare landscape.
Autoantibody determination plays an important role in the diagnosis and differentiation of autoimmune bullous dermatoses (AIBD). Various autoantibodies against skin structures can be detected by serological methods such as indirect immunofluorescence (IIF) and ELISA.
Arboviruses, or arthropod-borne viruses, are on the march globally. Increased urbanisation and international travel facilitate the spread of mosquito vectors and hence the viral diseases they carry.
Sexually transmitted infections (STIs) are a major and growing health problem in all parts of the world. According to the World Health Organisation (WHO) more than one million STIs are acquired worldwide every day. Untreated, they can lead to serious long-term sequelae, especially infertility.
Advances in medicine in the 17th century provided the foundation for diagnostic laboratory testing. The discovery of the circulation of blood by William Harvey and subsequent development of procedures to withdraw blood from a patient's vein for therapeutic purposes have enabled physicians to utilise blood to detect and monitor disease.
Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are distinct genetic disorders caused by lack of expression of paternally (PWS) or maternally (AS) imprinted genes in the 15q11–15q13 region, which is known as the Prader-Willi/Angelman syndrome critical region (PWASCR).
Since the announcement of the first working draft of the Human Genome on June 26, 2000, then President of the United States, Mr Bill Clinton had declared, “Genome Science will have a real impact on our lives - and even more, on the lives of our children.
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